In this NCS Podcast Hot Topics episode, host Richard Choi, DO, FNCS, discusses groundbreaking research on cerebrospinal fluid (CSF) filtration after aneurysmal subarachnoid hemorrhage with Katharina Busl, MD, MS, FNCS, division chief of neurocritical care at the University of Florida.

The episode explores the PILLAR XT Trial, which evaluates a dual-lumen intrathecal catheter designed to filter CSF and remove red blood cells and inflammatory byproducts more effectively. Drs. Busl and Choi examine the rationale behind CSF drainage, how prior research shaped this work, and what early results reveal about feasibility, safety, and clinical outcomes.